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1

Correlation of FCGR3A and EGFR germline polymorphisms with the efficacy of cetuximab in KRAS wild-type metastatic colorectal cancer

Jan Pander, Hans Gelderblom, Ninja F. Antonini, Jolien Tol, Johan H.J.M. van Krieken, Tahar van der Straaten, Cornelis J.A. Punt, Henk-Jan Guchelaar

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

2

Exploratory analysis of 1936 SNPs in ADME genes for association with busulfan clearance in adult hematopoietic stem cell recipients

ten Brink, Marloes H., Swen, Jesse J., Böhringer, Stefan, Wessels, Judith A.M., van der Straaten, Tahar, Marijt, Erik W.A., von dem Borne, Peter A., Zwaveling, Juliëtte, Guchelaar, Henk-Jan

Journal:

Pharmacogenetics and Genomics

Year:

2013

Language:

english

File:

PDF, 532 KB

english, 2013

3

Evidence for qualified quantitative mRNA analysis in formalin-fixed and paraffin-embedded colorectal carcinoma cells and tissue

Xiaobo Lu, Tahar van der Straaten, Marco Tiller, Xiaoxia Li

Journal:

Journal of Clinical Laboratory Analysis

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

4

ERCC1 and XPD/ERCC2 Polymorphisms’ Predictive Value of Oxaliplatin-Based Chemotherapies in Advanced Colorectal Cancer has an Ethnic Discrepancy: A Meta-analysis

Xiaobo Lu, Sha Xiao, Cuihong Jin, Tahar van der Straaten, Xiaoxia Li

Journal:

Journal of Clinical Laboratory Analysis

Year:

2012

Language:

english

File:

PDF, 464 KB

english, 2012

5

Responses to reactive oxygen intermediates and virulence of Salmonella typhimurium

Riny Janssen, Tahar van der Straaten, Angela van Diepen, Jaap T. van Dissel

Journal:

Microbes and Infection

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

6

Expression of β-defensin-1 in chimpanzee (Pan troglodytes) airways

Louise A. Duits, Jan A.M. Langermans, Sunita Paltansing, Tahar Van Der Straaten, Richard A.W. Vervenne, Patrice A. Frost, Pieter S. Hiemstra, Alan W. Thomas, Peter H. Nibbering

Journal:

Journal of Medical Primatology

Year:

2000

Language:

english

File:

PDF, 187 KB

english, 2000

7

Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib

Neeltje Steeghs, Ron H. J. Mathijssen, Judith A. M. Wessels, Anne-Joy de Graan, Tahar van der Straaten, Mariangela Mariani, Bernard Laffranchi, Silvia Comis, Maja J. A. de Jonge, Hans Gelderblom, Henk

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 164 KB

english, 2011

8

Criteria for the selection of single nucleotide polymorphisms in pathway pharmacogenetics: TNF inhibitors as a case study

Wouter M. Kooloos, Judith A.M. Wessels, Tahar van der Straaten, Tom W.J. Huizinga, Henk-Jan Guchelaar

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

9

Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis

Kooloos, Wouter M, Wessels, Judith AM, van der Straaten, Tahar, Allaart, Cornelia F, Huizinga, Tom WJ, Guchelaar, Henk-Jan

Journal:

Pharmacogenomics

Year:

2010

Language:

english

File:

PDF, 770 KB

english, 2010

10

Almost the entire 5′ non-translated region of hepatitis C virus is required for cap-independent translation

René Rijnbrand, Peter Bredenbeek, Tahar van der Straaten, Linda Whetter, Geneviève Inchauspé, Stanley Lemon, Willy Spaan

Journal:

Year:

1995

Language:

english

File:

PDF, 512 KB

english, 1995

11

Glutathione-S-transferase pi (GSTP1) codon 105 polymorphism is not associated with oxaliplatin efficacy or toxicity in advanced colorectal cancer patients

Dina M. Kweekel, Hans Gelderblom, Ninja F. Antonini, Tahar Van der Straaten, Johan W.R. Nortier, Cornelis J.A. Punt, Henk-Jan Guchelaar

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 136 KB

english, 2009

12

Population Pharmacokinetics and Pharmacogenetics of Everolimus in Renal Transplant Patients

Dirk Jan A. R. Moes, Rogier R. Press, Jan den Hartigh, Tahar van der Straaten, Johan W. de Fijter, Prof. Dr Henk-Jan Guchelaar

Journal:

Clinical Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 251 KB

english, 2012

13

Excision repair of BPDE-adducts in human lymphocytes: diminished capacity associated with ERCC1 C8092A (rs3212986) polymorphism

Yu, Tao, Liu, Yanhua, Lu, Xiaobo, Xiao, Sha, Cai, Yuan, Jin, Cuihong, Liu, Qiufang, Yang, Jinghua, Wu, Shengwen, Bao, Xiaoyan, Pan, Liang, Straaten, Tahar

Journal:

Archives of Toxicology

Year:

2013

Language:

english

File:

PDF, 358 KB

english, 2013

14

CYP2D6 genotype in relation to hot flashes as tamoxifen side effect in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial

Dezentjé, Vincent O., Gelderblom, Hans, Schaik, Ron H. N., Vletter-Bogaartz, Judith M., Straaten, Tahar, Wessels, Judith A. M., Kranenbarg, Elma Meershoek-Klein, Berns, Els M., Seynaeve, Caroline, Put

Journal:

Breast Cancer Research and Treatment

Year:

2014

Language:

english

File:

PDF, 370 KB

english, 2014

15

Concordance of genotype for polymorphisms in DNA isolated from peripheral blood and colorectal cancer tumor samples

van Huis-Tanja, Lieke, Kweekel, Dinemarie, Gelderblom, Hans, Koopman, Miriam, Punt, Kees, Guchelaar, Henk-Jan, van der Straaten, Tahar

Journal:

Pharmacogenomics

Year:

2013

Language:

english

File:

PDF, 774 KB

english, 2013

16

Excision Repair Cross-Complementation group 1 (ERCC1) C118T SNP does not affect cellular response to oxaliplatin

van Huis-Tanja, Lieke H., Kweekel, Dina M., Lu, Xiaobo, Franken, Kees, Koopman, Miriam, Gelderblom, Hans, Antonini, Ninja F., Punt, Cornelis J.A., Guchelaar, Henk-Jan, van der Straaten, Tahar

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

17

Germline variants in the CYP19A1 gene are related to specific adverse events in aromatase inhibitor users: a substudy of Dutch patients in the TEAM trial

Fontein, Duveken B. Y., Houtsma, Daniel, Nortier, Johan W. R., Baak-Pablo, Renee F., Kranenbarg, Elma Meershoek-Klein, Straaten, Tahar R. J. H. M., Putter, Hein, Seynaeve, Caroline, Gelderblom, Hans,

Journal:

Breast Cancer Research and Treatment

Year:

2014

Language:

english

File:

PDF, 422 KB

english, 2014

18

Multiplex Pyrosequencing of Two Polymorphisms in DNA Repair Gene XRCC1

van der Straaten, Tahar, Kweekel, Dinemarie, Tiller, Marco, Bogaartz, Judith, Guchelaar, Henk-Jan

Journal:

The Journal of Molecular Diagnostics

Year:

2006

Language:

english

File:

PDF, 535 KB

english, 2006

19

Genotyping of DNA Samples Isolated from Formalin-Fixed Paraffin-Embedded Tissues Using Preamplification

Baak-Pablo, Renee, Dezentje, Vincent, Guchelaar, Henk-Jan, van der Straaten, Tahar

Journal:

The Journal of Molecular Diagnostics

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

20

High-Quality Genotyping Data from Formalin-Fixed, Paraffin-Embedded Tissue on the Drug Metabolizing Enzymes and Transporters Plus Array

Vos, Hanneke I., van der Straaten, Tahar, Coenen, Marieke J.H., Flucke, Uta, te Loo, D. Maroeska W.M., Guchelaar, Henk-Jan

Journal:

The Journal of Molecular Diagnostics

Year:

2015

Language:

english

File:

PDF, 377 KB

english, 2015

21

Effect of genetic variants GSTA1 and CYP39A1 and age on busulfan clearance in pediatric patients undergoing hematopoietic stem cell transplantation

ten Brink, Marloes H, van Bavel, Tom, Swen, Jesse J, Straaten, Tahar van der, Bredius, Robbert GM, Lankester, Arjan C, Zwaveling, Juliëtte, Guchelaar, Henk-Jan

Journal:

Pharmacogenomics

Year:

2013

Language:

english

File:

PDF, 890 KB

english, 2013

22

Impact of ABCG2 polymorphisms on the clinical outcome and toxicity of gefitinib in non-small-cell lung cancer patients

Lemos, Clara, Giovannetti, Elisa, Zucali, Paolo A, Assaraf, Yehuda G, Scheffer, George L, van der Straaten, Tahar, D’Incecco, Armida, Falcone, Alfredo, Guchelaar, Henk-Jan, Danesi, Romano, Santoro, Ar

Journal:

Pharmacogenomics

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

23

Next-Generation Sequencing: Current Technologies and Applications . Edited by Jianping Xu

van der Straaten, Tahar

Journal:

Year:

2015

Language:

english

File:

PDF, 151 KB

english, 2015

24

A novel specific pyrosequencing method for genotyping FCGR3A rs396991 without coamplification of homologous gene FCGR3B

van der Straaten, Tahar, Martijn, Richender, el Hajoui, Toufik, Baak-Pablo, Renee, Guchelaar, Henk-Jan

Journal:

Pharmacogenetics and Genomics

Year:

2013

Language:

english

File:

PDF, 426 KB

english, 2013

25

FcGR genetic polymorphisms and the response to adalimumab in patients with rheumatoid arthritis

Dávila-Fajardo, Cristina Lucía, van der Straaten, Tahar, Baak-Pablo, Rene, Medarde Caballero, Catalina, Cabeza Barrera, Jose, Huizinga, Tom W, Guchelaar, Henk-Jan, Swen, Jesse J

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

26

Alternative methods to a TaqMan assay to detect a tri-allelic single nucleotide polymorphism rs757210 in the HNF1β gene

Swen, Jesse J., Baak-Pablo, Renee F., Guchelaar, Henk-Jan, van der Straaten, Tahar

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2012

Language:

english

File:

PDF, 565 KB

english, 2012

27

GenoChip CYP2D6 macroarray as a method to genotype for CYP2D6 variants: results of a validation study in a Caucasian population

Bank, Paul CD, Swen, Jesse J, Guchelaar, Henk-Jan, van der Straaten, Tahar

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.91 MB

english, 2015

28

Use of plasmid-derived external quality control samples in pharmacogenetic testing

van der Straaten, Tahar, Swen, Jesse, Baak-Pablo, Renee, Guchelaar, Henk-Jan

Journal:

Pharmacogenomics

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

29

Influence of the d3-Growth Hormone (GH) Receptor Isoform on Short-Term and Long-Term Treatment Response to GH Replacement in GH-Deficient Adults

van der Klaauw, Agatha A., van der Straaten, Tahar, Baak-Pablo, Renee, Biermasz, Nienke R., Guchelaar, Henk-Jan, Pereira, Alberto M., Smit, Johannes W. A., Romijn, Johannes A.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 96 KB

english, 2008

30

The challenges of developing a ‘medical-grade’ genome

van der Straaten, Tahar, Guchelaar, Henk-Jan, Swen, Jesse J

Journal:

Pharmacogenomics

Year:

2012

Language:

english

File:

PDF, 868 KB

english, 2012

31

Genetic Techniques for Pharmacogenetic Analyses

Straaten, Tahar, van Schaik, Ron

Journal:

Current Pharmaceutical Design

Year:

2010

Language:

english

File:

PDF, 134 KB

english, 2010

32

The ERCC2/XPD Lys751Gln polymorphism affects DNA repair of benzo[a]pyrene induced damage, tested in an in vitro model

Xiao, Sha, Cui, Su, Lu, Xiaobo, Guan, Yangyang, Li, Dandan, Liu, Qiufang, Cai, Yuan, Jin, Cuihong, Yang, Jinghua, Wu, Shengwen, van der Straaten, Tahar

Journal:

Toxicology in Vitro

Year:

2016

Language:

english

File:

PDF, 740 KB

english, 2016

33

Exploring genetic and non-genetic risk factors for delayed graft function, acute and subclinical rejection in renal transplant recipients

Moes, Dirk Jan A. R., Press, Rogier R., Ackaert, Oliver, Ploeger, Bart A., Bemelman, Frederike J., Diack, Cheikh, Wessels, Judith A. M., van der Straaten, Tahar, Danhof, Meindert, Sanders, Jan-Stephan

Journal:

British Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 837 KB

english, 2016

34

Explaining Variability in Tacrolimus Pharmacokinetics to Optimize Early Exposure in Adult Kidney Transplant Recipients

Press, Rogier R, Ploeger, Bart A, Hartigh, Jan den, Straaten, Tahar van der, Pelt, Johannes van, Danhof, Meindert, Fijter, Johan W de, Guchelaar, Henk-Jan

Journal:

Therapeutic Drug Monitoring

Year:

2009

Language:

english

File:

PDF, 365 KB

english, 2009

35

Gene–gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis

Dervieux, Thierry, Wessels, Judith A.M., van der Straaten, Tahar, Penrod, Nadia, Moore, Jason H., Guchelaar, Henk-Jan, Kremer, Joel M.

Journal:

Pharmacogenetics and Genomics

Year:

2009

Language:

english

File:

PDF, 250 KB

english, 2009

36

Genotypes of CYP2C8 and FGD4 and their association with peripheral neuropathy or early dose reduction in paclitaxel-treated breast cancer patients

Lam, Siu W, Frederiks, Charlotte N, van der Straaten, Tahar, Honkoop, Aafke H, Guchelaar, Henk-Jan, Boven, Epie

Journal:

British Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 233 KB

english, 2016

37

Genetic polymorphisms in 19q13.3 genes associated with alteration of repair capacity to BPDE-DNA adducts in primary cultured lymphocytes

Xiao, Mingyang, Xiao, Sha, Straaten, Tahar van der, Xue, Ping, Zhang, Guopei, Zheng, Xiao, Zhang, Qianye, Cai, Yuan, Jin, Cuihong, Yang, Jinghua, Wu, Shengwen, Zhu, Guolian, Lu, Xiaobo

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2016

Language:

english

File:

PDF, 689 KB

english, 2016

38

Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing

Buermans, Henk P.J., Vossen, Rolf H.A.M., Anvar, Seyed Yahya, Allard, William G., Guchelaar, Henk-Jan, White, Stefan J., den Dunnen, Johan T., Swen, Jesse J., van der Straaten, Tahar

Journal:

Year:

2017

Language:

english

File:

PDF, 834 KB

english, 2017

39

ERCC2/XPD Lys751Gln alter DNA repair efficiency of platinum-induced DNA damage through P53 pathway

Zhang, Guopei, Guan, Yangyang, Zhao, Yuejiao, van der Straaten, Tahar, Xiao, Sha, Xue, Ping, Zhu, Guolian, Liu, Qiufang, Cai, Yuan, Jin, Cuihong, Yang, Jinghua, Wu, Shengwen, Lu, Xiaobo

Journal:

Chemico-Biological Interactions

Year:

2017

Language:

english

File:

PDF, 2.24 MB

english, 2017

40

Centres of Excellence Course in Pharmacogenetics, 25–28 June 2012

Dávila-Fajardo, Cristina Lucía, Swen, Jesse J, van der Straaten, Tahar, Guchelaar, Henk-Jan

Journal:

European Journal of Hospital Pharmacy Science and Practice

Year:

2013

Language:

english

File:

PDF, 52 KB

english, 2013

41

Single-nucleotide polymorphisms in the genes of CES2, CDA and enzymatic activity of CDA for prediction of the efficacy of capecitabine-containing chemotherapy in patients with metastatic breast cancer

Lam, Siu W., van der Noort, Vincent, van der Straaten, Tahar, Honkoop, Aafke H., Peters, Godefridus J., Guchelaarc, Henk-Jan, Boven, Epie

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 604 KB

english, 2017

42

Genetic polymorphisms in angiogenesis-related genes are associated with worse progression-free survival of patients with advanced gastrointestinal stromal tumours treated with imatinib

Verboom, Michiel C., Kloth, Jacqueline S.L., Swen, Jesse J., van der Straaten, Tahar, Bovée, Judith V.M.G., Sleijfer, Stefan, Reyners, Anna K.L., Mathijssen, Ron H.J., Guchelaar, Henk-Jan, Steeghs, Ne

Journal:

European Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 295 KB

english, 2017

43

Genome Wide Association Study for Predictors of Progression Free Survival in Patients on Capecitabine, Oxaliplatin, Bevacizumab and Cetuximab in First-Line Therapy of Metastatic Colorectal Cancer

Pander, Jan, van Huis-Tanja, Lieke, Böhringer, Stefan, van der Straaten, Tahar, Gelderblom, Hans, Punt, Cornelis, Guchelaar, Henk-Jan, Gerger, Armin

Journal:

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

44

The pediatric acenocoumarol dosing algorithm: The Children Anticoagulation and Pharmacogenetics Study

Maagdenberg, Hedy, Bierings, Marc B., van Ommen, C. Heleen, van der Meer, Felix J.M., Appel, Inge M., Tamminga, Rienk Y.J., le Cessie, Saskia, Swen, Jesse J., van der Straaten, Tahar, de Boer, Anthoni

Journal:

Journal of Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

45

Effects of age and genetic variations in VKORC1 , CYP2C9 and CYP3A4 on the phenprocoumon dose in pediatric patients

Maagdenberg, Hedy, Bierings, Marc B, van Ommen, C Heleen, van der Meer, Felix JM, Appel, Inge M, Tamminga, Rienk YJ, Cessie, Saskia le, Swen, Jesse J, der Straaten, Tahar van, Boer, Anthonius de, Mait

Journal:

Pharmacogenomics

Year:

2018

Language:

english

File:

PDF, 573 KB

english, 2018